Chalice Dungeon Sequence
To reach Yharnam, Pthumerian Queen, you must complete the static Chalice Dungeons in order:
Dungeon Step 1
Pthumeru Chalice & Central Pthumeru
Obtained from Blood-starved Beast in Old Yharnam. Clear all 3 layers to receive the Next Chalice.
Dungeon Step 2
Lower Pthumeru & Aygdala Defiled Chalice
Obtain the Defiled Chalice from Amygdala in Nightmare Frontier. Note: Defiled Chalice reduces your max HP by 50%. Practice dodge timing for Watchdog of the Old Lords.
Dungeon Step 3
Great Pthumeru Ihyll Chalice
Layer 3 boss is Yharnam, Pthumerian Queen. Defeating her yields the gold trophy "Yharnam, Pthumerian Queen" and pushes you one step closer to the Platinum.
Third Umbilical Cord Locations
To unlock the "Childhood's Beginning" secret ending trophy, consume 3 of the 4 available Third Cords before fighting Gehrman, the First Hunter:
- Defeat Mergo's Wet Nurse in Nightmare of Mensis (Mandatory Story Cord).
- Abandon workshop secret area inside the Old Abandoned Workshop.
- Send Arianna to Iosefka's Clinic or Oedon Chapel and defeat her infant after Micolash.
- Kill Iosefka in her clinic AFTER defeating Rom, the Vacuous Spider.